I've only seen the trailer for 2oolander, but even I know that Owen Wilson and Ben Stiller play...semi offensive buffoons. I'm sure that Stiller worked the scenes that give his characters a "lesson" in sensitivity.
I find it odd that someone who hasn't seen the full context of a movie can judge it or wants to boycott it. (Then again, I loath most critics for their false participation).
Boycotting something like a film is the equivalent to book burning. It tells me that you are afraid that your message isn't strong enough, or true enough, to withstand mockery.
It tells me that you are afraid of ideas. Ideas can change, or be wrong.
On a different note: If a person that identifies as the gender they were born with isn't allowed to play a transgender in a comedy then the opposite should be true. Trans can't play cis gender people, straights can't play homosexual roles, and homosexuals can't play straight roles (sorry NPH).
And I would still rather watch Cumberbatch play ANY role than some model as was suggested.
I'll see this move regardless of who is in it, because I enjoyed the first one. I'll leave political agenda at the door and judge for myself what I find offensive or not.
I invite you to do the same.